Product:
IBM DB2 Data Studio 4.1.1
Windows 2012 R2 Server
DB2 database

Problem:
Get a error when I start the program Data Studio 4.1.1 Client

Error Message:
Locking is not possible in the directory “D:\xxxx…. ” A common reason is that the file system or Runtime Environment does not support file locking for that location. Please choose a different location, or disable file locking passing “-Dosgi.locking=none” as a VM argument. ….

Possible Solution:
Right click on the icon for Data Studio 4.1.1 Client and start the program “Run As Administrator”.

During installation the Windows environment was not setup to run in a “multiuser environment”.